Warren Wen Selected Research

Hydrocodone (Dihydrocodeinone)

1/2017	Long-term effectiveness and safety of once-daily, single-entity, extended-release hydrocodone in patients of ≥75 years of age with moderate to severe nonmalignant and nonneuropathic pain.
1/2017	Evaluation of the Ototoxicity Potential of Once-Daily, Single-Entity Hydrocodone in Patients with Chronic Pain: Results of Two Phase-3 Clinical Studies.
1/2017	Efficacy and Safety of Once-Daily Extended-Release (ER) Hydrocodone in Individuals Previously Receiving ER Morphine for Chronic Pain.
11/2015	Pain intensity and interference with functioning and well-being in subgroups of patients with chronic pain treated with once-daily hydrocodone tablets.
7/2015	12-Month safety and effectiveness of once-daily hydrocodone tablets formulated with abuse-deterrent properties in patients with moderate to severe chronic pain.
1/2015	A multicenter, randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of single-entity, once-daily hydrocodone tablets in patients with uncontrolled moderate to severe chronic low back pain.
1/2015	Efficacy and safety of once-daily, extended-release hydrocodone in individuals previously receiving hydrocodone/acetaminophen combination therapy for chronic pain.
6/2012	A randomized, 14-day, double-blind study evaluating conversion from hydrocodone/acetaminophen (Vicodin) to buprenorphine transdermal system 10 μg/h or 20 μg/h in patients with osteoarthritis pain.

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Warren Wen Research Topics

Disease

11	Pain (Aches) 01/2017 - 06/2012
8	Low Back Pain (Lumbago) 04/2016 - 12/2011
7	Chronic Pain 01/2017 - 05/2013
3	Pruritus (Itching) 12/2021 - 01/2020
2	Chronic Renal Insufficiency 01/2021 - 01/2020
2	Vomiting 01/2020 - 07/2015
2	Dizziness (Lightheadedness) 01/2020 - 07/2015
1	Diarrhea 01/2020
1	Body Weight (Weight, Body) 01/2020
1	Ototoxicity 01/2017
1	Deafness (Deaf Mutism) 01/2017
1	Sensorineural Hearing Loss 01/2017
1	Neuralgia (Stump Neuralgia) 11/2015
1	Headache (Headaches) 07/2015
1	Fatigue 07/2015
1	Constipation 07/2015
1	Sleepiness 07/2015
1	Nausea 07/2015
1	Osteoarthritis 06/2012

Drug/Important Bio-Agent (IBA)

11	Opioid Analgesics (Opioids)IBA 01/2017 - 12/2011
9	Buprenorphine (Subutex)FDA LinkGeneric 04/2016 - 12/2011
8	Hydrocodone (Dihydrocodeinone)FDA LinkGeneric 01/2017 - 06/2012
5	TabletsIBA 01/2017 - 01/2015
4	Analgesics (Analgesic Drugs)IBA 09/2016 - 06/2012
3	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2017 - 06/2012
1	difelikefalinIBA 01/2020
1	kappa Opioid Receptors (kappa Opioid Receptor)IBA 01/2020
1	Morphine (MS Contin)FDA LinkGeneric 01/2017
1	ORALIT (ORS)IBA 12/2014
1	Pharmaceutical PreparationsIBA 05/2013
1	hydrocodone drug combination acetaminophen (Vicodin ES)FDA LinkGeneric 06/2012

Therapy/Procedure

3	Renal Dialysis (Hemodialysis) 12/2021 - 01/2020
2	Therapeutics 09/2016 - 01/2015
2	Activities of Daily Living (ADL) 07/2015 - 12/2014
1	Pain Management 01/2017
1	Precision Medicine 09/2016
1	Analgesia 01/2015
1	Transdermal Patch 12/2011